Fig. 1From: A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scoresLocus Zoom plots showing the association of SNPs in the regions of novel loci with cognitive domains. The SNP with the lowest p-value at each locus is indicated with a purple diamond. Computed estimates of linkage disequilibrium (r2) of SNPs in the region with top-ranked SNP are color-coded according to the key. Vertical blue lines indicate locations of high recombination rates. Locations of genes in the region are shown below the diagram. a Association of rs157405 with executive function in the community-based cohorts. b Association of rs705353 with language in the clinic-based cohorts. c Association of rs117523305 with memory in the community-based cohorts. d Association of rs145012974 with language in the total sample. e Association of rs5848 with memory in the total sampleBack to article page