Molecular Neurodegeneration

Featured video: The role of non-coding RNAs in Alzheimer’s disease

Video abstract summarizing new research published in Molecular Neurodegeneration. "Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer’s disease", De Jager et al. 2017

Content type: Research article
| 22 June 2018

Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Authors: Lodewijk J. A. Toonen, Maurice Overzier, Melvin M. Evers, Leticia G. Leon, Sander A. J. van der Zeeuw, Hailiang Mei, Szymon M. Kielbasa, Jelle J. Goeman, Kristina M. Hettne, Olafur Th. Magnusson, Marion Poirel, Alexandre Seyer, Peter A. C. ‘t Hoen and Willeke M. C. van Roon-Mom
Content type: Research article
| 22 June 2018

Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency

Authors: Andrew E. Arrant, Alexandra M. Nicholson, Xiaolai Zhou, Rosa Rademakers and Erik D. Roberson
Content type: Research article
| 1 June 2018

Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis

Authors: Tatyana A. Shelkovnikova, Michail S. Kukharsky, Haiyan An, Pasquale Dimasi, Svetlana Alexeeva, Osman Shabir, Paul R. Heath and Vladimir L. Buchman
Content type: Research article
| 1 June 2018

The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer’s disease

Authors: Paul J. Cheng-Hathaway, Erin G. Reed-Geaghan, Taylor R. Jay, Brad T. Casali, Shane M. Bemiller, Shweta S. Puntambekar, Victoria E. von Saucken, Roxanne Y. Williams, J. Colleen Karlo, Miguel Moutinho, Guixiang Xu, Richard M. Ransohoff, Bruce T. Lamb and Gary E. Landreth
Content type: Review
| 24 May 2018

Targeting energy metabolism via the mitochondrial pyruvate carrier as a novel approach to attenuate neurodegeneration

Authors: Emmanuel Quansah, Wouter Peelaerts, J. William Langston, David K. Simon, Jerry Colca and Patrik Brundin

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Content type: Research article
| 24 August 2012

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Authors: Karin M Danzer, Lisa R Kranich, Wolfgang P Ruf, Ozge Cagsal-Getkin, Ashley R Winslow, Liya Zhu, Charles R Vanderburg and Pamela J McLean
Content type: Research article
| 12 April 2007

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1polymorphisms

Authors: Suzanne E Wahrle, Aarti R Shah, Anne M Fagan, Scott Smemo, John SK Kauwe, Andrew Grupe, Anthony Hinrichs, Kevin Mayo, Hong Jiang, Leon J Thal, Alison M Goate and David M Holtzman
Content type: Review
| 22 November 2013

Drosophila melanogaster as a model organism for Alzheimer’s disease

Authors: Katja Prüßing, Aaron Voigt and Jörg B Schulz
Content type: Review
| 21 June 2013

Fluid biomarkers in Alzheimer’s disease – current concepts

Authors: Christoffer Rosén, Oskar Hansson, Kaj Blennow and Henrik Zetterberg
Content type: Review
| 15 November 2007

The Alzheimer's disease β-secretase enzyme, BACE1

Authors: Sarah L Cole and Robert Vassar

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Editors-in-Chief

Guojun Bu, Mayo Clinic, USA
Huaxi Xu, Sanford Burnham Prebys Medical Discovery Institute, USA

Aims and scope

Molecular Neurodegeneration is an open access, peer-reviewed journal that encompasses all aspects of neurodegeneration research at the molecular and cellular levels.

Society partner

Molecular Neurodegeneration is the official journal of the BrightFocus Foundation.

About BrightFocus | Research | Grants

Upcoming conference

The 5^th international conference on Molecular Neurodegeneration
ICMN 2018: Overlapping Pathologies and Common Mechanisms

June 11 – 13, 2018

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News from Alzforum

Girl Power? In Mice, Female Microglia Protect Against Ischemic Injury

22 June 2018
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22 June 2018
Aberrant Networks in Alzheimer’s Tied to Herpes Viruses

21 June 2018

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2016

Thematic series
Molecular Neurodegeneration
Novel Systems and Emerging Concepts
Molecular Neurodegeneration
Collection published: 7 December 2016

2014

Thematic series
Molecular Neurodegeneration
Basic biology and disease pathways
Molecular Neurodegeneration
Collection published: 12 September 2014

Molecular Neurodegeneration

Featured video: The role of non-coding RNAs in Alzheimer’s disease

Articles

Transcriptional profiling and biomarker identification reveal tissue specific effects of expanded ataxin-3 in a spinocerebellar ataxia type 3 mouse model

Partial Tmem106b reduction does not correct abnormalities due to progranulin haploinsufficiency

Protective paraspeckle hyper-assembly downstream of TDP-43 loss of function in amyotrophic lateral sclerosis

The Trem2 R47H variant confers loss-of-function-like phenotypes in Alzheimer’s disease

Targeting energy metabolism via the mitochondrial pyruvate carrier as a novel approach to attenuate neurodegeneration

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1polymorphisms

Drosophila melanogaster as a model organism for Alzheimer’s disease

Fluid biomarkers in Alzheimer’s disease – current concepts

The Alzheimer's disease β-secretase enzyme, BACE1

Latest Tweets

Editors-in-Chief

Aims and scope

Society partner

Upcoming conference

News from Alzforum

Girl Power? In Mice, Female Microglia Protect Against Ischemic Injury

α-Synuclein Antibody Appears Safe, Reaches Brain

Aberrant Networks in Alzheimer’s Tied to Herpes Viruses

Latest collections

2016

2014

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Molecular Neurodegeneration

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