Molecular Neurodegeneration

Rice et al. 2020

Featured Short Report: Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model

Heather C. Rice, …, Bart De Strooper

Chen et al. 2020

Featured Research: Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy

Xu Chen, …, Ana Maria Cuervo and Li Gan

An et al. 2019

Featured Research: Longitudinal and nonlinear relations of dietary and Serum cholesterol in midlife with cognitive decline: results from EMCOA study

Yu An, Xiaona Zhang, …, Zhongsheng Qin and Rong Xiao

Pandey et al. 2019

Featured Research: Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer’s disease

Ravi S. Pandey, …, Gareth R. Howell and Gregory W. Carter

A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles

Authors: Jian-Guo Li, Jin Chiu, Mercy Ramanjulu, Benjamin E. Blass and Domenico Praticò

Content type: Research article

22 January 2020
Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway

Authors: Jae-Hyeon Park, Jeremy D. Burgess, Ayman H. Faroqi, Natasha N. DeMeo, Fabienne C. Fiesel, Wolfdieter Springer, Marion Delenclos and Pamela J. McLean

Content type: Research article

13 January 2020
VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice

Authors: Farida El Gaamouch, Mickael Audrain, Wei-Jye Lin, Noam Beckmann, Cheng Jiang, Siddharth Hariharan, Peter S. Heeger, Eric E. Schadt, Sam Gandy, Michelle E. Ehrlich and Stephen R. Salton

Content type: Research article

10 January 2020
Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model

Authors: Heather C. Rice, Gabriele Marcassa, Iordana Chrysidou, Katrien Horré, Tracy L. Young-Pearse, Ulrike C. Müller, Takashi Saito, Takaomi C. Saido, Robert Vassar, Joris de Wit and Bart De Strooper

Content type: Short report

8 January 2020
Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy

Authors: Xu Chen, Yaqiao Li, Chao Wang, Yinyan Tang, Sue-Ann Mok, Richard M. Tsai, Julio C. Rojas, Anna Karydas, Bruce L. Miller, Adam L. Boxer, Jason E. Gestwicki, Michelle Arkin, Ana Maria Cuervo and Li Gan

Content type: Research article

6 January 2020

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Exosomal cell-to-cell transmission of alpha synuclein oligomers

Authors: Karin M Danzer, Lisa R Kranich, Wolfgang P Ruf, Ozge Cagsal-Getkin, Ashley R Winslow, Liya Zhu, Charles R Vanderburg and Pamela J McLean

Content type: Research article

24 August 2012
Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1polymorphisms

Authors: Suzanne E Wahrle, Aarti R Shah, Anne M Fagan, Scott Smemo, John SK Kauwe, Andrew Grupe, Anthony Hinrichs, Kevin Mayo, Hong Jiang, Leon J Thal, Alison M Goate and David M Holtzman

Content type: Research article

12 April 2007
Drosophila melanogaster as a model organism for Alzheimer’s disease

Authors: Katja Prüßing, Aaron Voigt and Jörg B Schulz

Content type: Review

22 November 2013
The Alzheimer's disease β-secretase enzyme, BACE1

Authors: Sarah L Cole and Robert Vassar

Content type: Review

15 November 2007
The SH-SY5Y cell line in Parkinson’s disease research: a systematic review

Authors: Helena Xicoy, Bé Wieringa and Gerard J.M. Martens

Content type: Review

24 January 2017

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Parkinson's Disease - A Series of Reviews

Molecular Neurodegeneration
Novel Systems and Emerging Concepts

Molecular Neurodegeneration
Basic biology and disease pathways

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The 6th International Conference on Molecular Neurodegeneration will focus on Glial and Vascular Contributions to Neurodegenerative Diseases.

Join us in Bangkok, Thailand on May 21-23 2020!
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Parkinson's disease - a series of reviews

Molecular Neurodegeneration presents a new thematic series, collating reviews on recent advances in Parkinson's Disease research.

Guest Edited by Mark Cookson and Ted Dawson, reviews will continue to publish throughout 2020. The collection can be read here.

About Us

The leading open access journal in the field of neurosciences, Molecular Neurodegeneration encompasses all aspects of neurodegeneration research at the molecular and cellular levels.

Editors-in-Chief:

Guojun Bu, Mayo Clinic, USA
Huaxi Xu, Sanford Burnham Prebys Medical Discovery Institute, USA

Molecular Neurodegeneration

Featured Short Report: Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model

Featured Research: Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy

Featured Research: Longitudinal and nonlinear relations of dietary and Serum cholesterol in midlife with cognitive decline: results from EMCOA study

Featured Research: Genetic perturbations of disease risk genes in mice capture transcriptomic signatures of late-onset Alzheimer’s disease

Articles

A pharmacological chaperone improves memory by reducing Aβ and tau neuropathology in a mouse model with plaques and tangles

Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway

VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice

Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model

Promoting tau secretion and propagation by hyperactive p300/CBP via autophagy-lysosomal pathway in tauopathy

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1polymorphisms

Drosophila melanogaster as a model organism for Alzheimer’s disease

The Alzheimer's disease β-secretase enzyme, BACE1

The SH-SY5Y cell line in Parkinson’s disease research: a systematic review

Editor highlights

Article collections

Parkinson's Disease - A Series of Reviews

Molecular Neurodegeneration
Novel Systems and Emerging Concepts

Molecular Neurodegeneration
Basic biology and disease pathways

Register now for ICMN2020

Parkinson's disease - a series of reviews

About Us

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Molecular Neurodegeneration

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