Molecular Neurodegeneration

Featured video: The role of non-coding RNAs in Alzheimer’s disease

Video abstract summarizing new research published in Molecular Neurodegeneration. "Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer’s disease", De Jager et al. 2017

Content type: Research article
| 13 November 2018

Functional alterations of myeloid cells during the course of Alzheimer’s disease

Authors: Aaron D. Thome, Alireza Faridar, David R. Beers, Jason R. Thonhoff, Weihua Zhao, Shixiang Wen, Belen Pascual, Joseph C. Masdeu and Stanley H. Appel
Content type: Research article
| 7 November 2018

Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis

Authors: Irene Zubiri, Vittoria Lombardi, Michael Bremang, Vikram Mitra, Giovanni Nardo, Rocco Adiutori, Ching-Hua Lu, Emanuela Leoni, Ping Yip, Ozlem Yildiz, Malcolm Ward, Linda Greensmith, Caterina Bendotti, Ian Pike and Andrea Malaspina
Content type: Research article
| 7 November 2018

A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model

Authors: Bin Zhang, Yuemang Yao, Anne-Sophie Cornec, Killian Oukoloff, Michael J. James, Pyry Koivula, John Q. Trojanowski, Amos B. Smith III, Virginia M.-Y. Lee, Carlo Ballatore and Kurt R. Brunden
Content type: Research article
| 19 October 2018

Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism

Authors: Qingyi Ma, Zhen Zhao, Abhay P Sagare, Yingxi Wu, Min Wang, Nelly Chuqui Owens, Philip B Verghese, Joachim Herz, David M Holtzman and Berislav V Zlokovic
Content type: Research article
| 17 October 2018

Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis

Authors: Takae Kiyama, Ching-Kang Chen, Steven W Wang, Ping Pan, Zhenlin Ju, Jing Wang, Shinako Takada, William H Klein and Chai-An Mao

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Content type: Research article
| 24 August 2012

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Authors: Karin M Danzer, Lisa R Kranich, Wolfgang P Ruf, Ozge Cagsal-Getkin, Ashley R Winslow, Liya Zhu, Charles R Vanderburg and Pamela J McLean
Content type: Research article
| 12 April 2007

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1polymorphisms

Authors: Suzanne E Wahrle, Aarti R Shah, Anne M Fagan, Scott Smemo, John SK Kauwe, Andrew Grupe, Anthony Hinrichs, Kevin Mayo, Hong Jiang, Leon J Thal, Alison M Goate and David M Holtzman
Content type: Review
| 22 November 2013

Drosophila melanogaster as a model organism for Alzheimer’s disease

Authors: Katja Prüßing, Aaron Voigt and Jörg B Schulz
Content type: Review
| 21 June 2013

Fluid biomarkers in Alzheimer’s disease – current concepts

Authors: Christoffer Rosén, Oskar Hansson, Kaj Blennow and Henrik Zetterberg
Content type: Review
| 15 November 2007

The Alzheimer's disease β-secretase enzyme, BACE1

Authors: Sarah L Cole and Robert Vassar

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Editors-in-Chief

Guojun Bu, Mayo Clinic, USA
Huaxi Xu, Sanford Burnham Prebys Medical Discovery Institute, USA

Aims and scope

Molecular Neurodegeneration is an open access, peer-reviewed journal that encompasses all aspects of neurodegeneration research at the molecular and cellular levels.

Society partner

Molecular Neurodegeneration is the official journal of the BrightFocus Foundation.

About BrightFocus | Research | Grants

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2016

Thematic series
Molecular Neurodegeneration
Novel Systems and Emerging Concepts
Molecular Neurodegeneration
Collection published: 7 December 2016

2014

Thematic series
Molecular Neurodegeneration
Basic biology and disease pathways
Molecular Neurodegeneration
Collection published: 12 September 2014

Molecular Neurodegeneration

Featured video: The role of non-coding RNAs in Alzheimer’s disease

Articles

Functional alterations of myeloid cells during the course of Alzheimer’s disease

Tissue-enhanced plasma proteomic analysis for disease stratification in amyotrophic lateral sclerosis

A brain-penetrant triazolopyrimidine enhances microtubule-stability, reduces axonal dysfunction and decreases tau pathology in a mouse tauopathy model

Blood-brain barrier-associated pericytes internalize and clear aggregated amyloid-β42 by LRP1-dependent apolipoprotein E isoform-specific mechanism

Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1polymorphisms

Drosophila melanogaster as a model organism for Alzheimer’s disease

Fluid biomarkers in Alzheimer’s disease – current concepts

The Alzheimer's disease β-secretase enzyme, BACE1

Editors-in-Chief

Aims and scope

Society partner

News from Alzforum

Trial-Ready Cohorts Take Shape in Europe and U.S.

Trials of Diabetes-Related Therapies: Mainly a Bust

Fits and Starts: Trial Results from the CTAD Conference

Latest collections

2016

2014

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2017 Journal Metrics

Molecular Neurodegeneration

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