Molecular Neurodegeneration

Marc Suárez-Calvet et al. 2018

Featured Research: Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

Marc Suárez-Calvet, Estrella Morenas-Rodríguez [...] Christian Haass

Yaping Shao and Weidong Le

Featured Review: Recent advances and perspectives of metabolomics-based investigations in Parkinson’s disease

Yaping Shao and Weidong Le

Maud Gratuze et al. 2018

Featured Review: New insights into the role of TREM2 in Alzheimer’s disease

Maud Gratuze, Cheryl E. G. Leyns and David M. Holtzman

Amanda McQuade et al. 2018

Featured Methodology: Development and validation of a simplified method to generate human microglia from pluripotent stem cells

Amanda McQuade, Morgan Coburn [...] Mathew Blurton-Jones

Content type: Review
| 16 January 2019

Emerging new roles of the lysosome and neuronal ceroid lipofuscinoses

Authors: Anil B. Mukherjee, Abhilash P. Appu, Tamal Sadhukhan, Sydney Casey, Avisek Mondal, Zhongjian Zhang and Maria B. Bagh
Content type: Review
| 11 January 2019

Recent advances and perspectives of metabolomics-based investigations in Parkinson’s disease

Authors: Yaping Shao and Weidong Le
Content type: Research article
| 11 January 2019

Glucose transporter 1 critically controls microglial activation through facilitating glycolysis

Authors: Luxi Wang, Sofia Pavlou, Xuan Du, Mohajeet Bhuckory, Heping Xu and Mei Chen
Content type: Research article
| 10 January 2019

Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

Authors: Marc Suárez-Calvet, Estrella Morenas-Rodríguez, Gernot Kleinberger, Kai Schlepckow, Miguel Ángel Araque Caballero, Nicolai Franzmeier, Anja Capell, Katrin Fellerer, Brigitte Nuscher, Erden Eren, Johannes Levin, Yuetiva Deming, Laura Piccio, Celeste M. Karch, Carlos Cruchaga, Leslie M. Shaw…
Content type: Research article
| 29 December 2018

Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration

Authors: Gregor Bieri, Kurt M. Lucin, Caitlin E. O’Brien, Hui Zhang, Saul A. Villeda and Tony Wyss-Coray

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Content type: Research article
| 24 August 2012

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Authors: Karin M Danzer, Lisa R Kranich, Wolfgang P Ruf, Ozge Cagsal-Getkin, Ashley R Winslow, Liya Zhu, Charles R Vanderburg and Pamela J McLean
Content type: Research article
| 12 April 2007

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1polymorphisms

Authors: Suzanne E Wahrle, Aarti R Shah, Anne M Fagan, Scott Smemo, John SK Kauwe, Andrew Grupe, Anthony Hinrichs, Kevin Mayo, Hong Jiang, Leon J Thal, Alison M Goate and David M Holtzman
Content type: Review
| 22 November 2013

Drosophila melanogaster as a model organism for Alzheimer’s disease

Authors: Katja Prüßing, Aaron Voigt and Jörg B Schulz
Content type: Review
| 15 November 2007

The Alzheimer's disease β-secretase enzyme, BACE1

Authors: Sarah L Cole and Robert Vassar
Content type: Review
| 21 June 2013

Fluid biomarkers in Alzheimer’s disease – current concepts

Authors: Christoffer Rosén, Oskar Hansson, Kaj Blennow and Henrik Zetterberg

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About Us

The leading open access journal in the field of neurosciences, Molecular Neurodegeneration encompasses all aspects of neurodegeneration research at the molecular and cellular levels.

Editors-in-Chief:

Guojun Bu, Mayo Clinic, USA
Huaxi Xu, Sanford Burnham Prebys Medical Discovery Institute, USA

Molecular Neurodegeneration
Novel Systems and Emerging Concepts

Molecular Neurodegeneration
Basic biology and disease pathways

News from Alzforum

Invasion of the Microtubules: Mutant Tau Deforms Neuronal Nuclei

19 January 2019
Deadline to Weigh In on New Biomarker Guidance Approaches

18 January 2019
Microtubule Regulator Connects TDP-43 to Axonal Dysfunction

18 January 2019

Molecular Neurodegeneration

Featured Research: Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

Featured Review: Recent advances and perspectives of metabolomics-based investigations in Parkinson’s disease

Featured Review: New insights into the role of TREM2 in Alzheimer’s disease

Featured Methodology: Development and validation of a simplified method to generate human microglia from pluripotent stem cells

Articles

Emerging new roles of the lysosome and neuronal ceroid lipofuscinoses

Recent advances and perspectives of metabolomics-based investigations in Parkinson’s disease

Glucose transporter 1 critically controls microglial activation through facilitating glycolysis

Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

Proteolytic cleavage of Beclin 1 exacerbates neurodegeneration

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1polymorphisms

Drosophila melanogaster as a model organism for Alzheimer’s disease

The Alzheimer's disease β-secretase enzyme, BACE1

Fluid biomarkers in Alzheimer’s disease – current concepts

About Us

Editors-in-Chief:

Article collections

Molecular Neurodegeneration
Novel Systems and Emerging Concepts

Molecular Neurodegeneration
Basic biology and disease pathways

News from Alzforum

Invasion of the Microtubules: Mutant Tau Deforms Neuronal Nuclei

Deadline to Weigh In on New Biomarker Guidance Approaches

Microtubule Regulator Connects TDP-43 to Axonal Dysfunction

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Molecular Neurodegeneration

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