Molecular Neurodegeneration

Marc Suárez-Calvet et al. 2018

Featured Research: Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

Marc Suárez-Calvet, Estrella Morenas-Rodríguez [...] Christian Haass

Yaping Shao and Weidong Le

Featured Review: Recent advances and perspectives of metabolomics-based investigations in Parkinson’s disease

Yaping Shao and Weidong Le

Outeiro et al. 2019

Featured Review: Dementia with Lewy bodies - an update and outlook

Tiago Fleming Outeiro, David J. Koss […] Ian McKeith

Amanda McQuade et al. 2018

Featured Methodology: Development and validation of a simplified method to generate human microglia from pluripotent stem cells

Amanda McQuade, Morgan Coburn [...] Mathew Blurton-Jones

Content type: Research article
| 15 February 2019

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Authors: Jeannie Chew, Casey Cook, Tania F. Gendron, Karen Jansen-West, Giulia del Rosso, Lillian M. Daughrity, Monica Castanedes-Casey, Aishe Kurti, Jeannette N. Stankowski, Matthew D. Disney, Jeffrey D. Rothstein, Dennis W. Dickson, John D. Fryer, Yong-Jie Zhang and Leonard Petrucelli
Content type: Methodology
| 8 February 2019

Differences in neurotropism and neurotoxicity among retrograde viral tracers

Authors: Leqiang Sun, Yajie Tang, Keji Yan, Jinsong Yu, Yanyan Zou, Weize Xu, Ke Xiao, Zhihui Zhang, Weiming Li, Beili Wu, Zhe Hu, Kening Chen, Zhen F. Fu, Jinxia Dai and Gang Cao
Content type: Research article
| 22 January 2019

Reduced presynaptic vesicle stores mediate cellular and network plasticity defects in an early-stage mouse model of Alzheimer’s disease

Authors: Shreaya Chakroborty, Evan S. Hill, Daniel T. Christian, Rosalind Helfrich, Shannon Riley, Corinne Schneider, Nicolas Kapecki, Sarah Mustaly-Kalimi, Figen A. Seiler, Daniel A. Peterson, Anthony R. West, Barbara M. Vertel, William N. Frost and Grace E. Stutzmann
Content type: Research article
| 22 January 2019

Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma

Authors: Pete A. Williams, Catherine E. Braine, Krishnakumar Kizhatil, Nicole E. Foxworth, Nicholas G. Tolman, Jeffrey M. Harder, Rebecca A. Scott, Gregory L. Sousa, Alyssa Panitch, Gareth R. Howell and Simon W. M. John
Content type: Review
| 21 January 2019

Dementia with Lewy bodies: an update and outlook

Authors: Tiago Fleming Outeiro, David J. Koss, Daniel Erskine, Lauren Walker, Marzena Kurzawa-Akanbi, David Burn, Paul Donaghy, Christopher Morris, John-Paul Taylor, Alan Thomas, Johannes Attems and Ian McKeith

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Content type: Research article
| 24 August 2012

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Authors: Karin M Danzer, Lisa R Kranich, Wolfgang P Ruf, Ozge Cagsal-Getkin, Ashley R Winslow, Liya Zhu, Charles R Vanderburg and Pamela J McLean
Content type: Research article
| 12 April 2007

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1polymorphisms

Authors: Suzanne E Wahrle, Aarti R Shah, Anne M Fagan, Scott Smemo, John SK Kauwe, Andrew Grupe, Anthony Hinrichs, Kevin Mayo, Hong Jiang, Leon J Thal, Alison M Goate and David M Holtzman
Content type: Review
| 22 November 2013

Drosophila melanogaster as a model organism for Alzheimer’s disease

Authors: Katja Prüßing, Aaron Voigt and Jörg B Schulz
Content type: Review
| 15 November 2007

The Alzheimer's disease β-secretase enzyme, BACE1

Authors: Sarah L Cole and Robert Vassar
Content type: Review
| 21 June 2013

Fluid biomarkers in Alzheimer’s disease – current concepts

Authors: Christoffer Rosén, Oskar Hansson, Kaj Blennow and Henrik Zetterberg

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About Us

The leading open access journal in the field of neurosciences, Molecular Neurodegeneration encompasses all aspects of neurodegeneration research at the molecular and cellular levels.

Editors-in-Chief:

Guojun Bu, Mayo Clinic, USA
Huaxi Xu, Sanford Burnham Prebys Medical Discovery Institute, USA

Molecular Neurodegeneration
Novel Systems and Emerging Concepts

Molecular Neurodegeneration
Basic biology and disease pathways

News from Alzforum

In Small Trial, EH301 Appears to Halt Progression of ALS

18 February 2019
Immune Cells Clog Capillaries in Mice, Disrupt Memory

16 February 2019
Studies Point to DNA Difficulties in ALS/FTD

16 February 2019

Molecular Neurodegeneration

Featured Research: Early increase of CSF sTREM2 in Alzheimer’s disease is associated with tau related-neurodegeneration but not with amyloid-β pathology

Featured Review: Recent advances and perspectives of metabolomics-based investigations in Parkinson’s disease

Featured Review: Dementia with Lewy bodies - an update and outlook

Featured Methodology: Development and validation of a simplified method to generate human microglia from pluripotent stem cells

Articles

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Differences in neurotropism and neurotoxicity among retrograde viral tracers

Reduced presynaptic vesicle stores mediate cellular and network plasticity defects in an early-stage mouse model of Alzheimer’s disease

Inhibition of monocyte-like cell extravasation protects from neurodegeneration in DBA/2J glaucoma

Dementia with Lewy bodies: an update and outlook

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1polymorphisms

Drosophila melanogaster as a model organism for Alzheimer’s disease

The Alzheimer's disease β-secretase enzyme, BACE1

Fluid biomarkers in Alzheimer’s disease – current concepts

About Us

Editors-in-Chief:

Article collections

Molecular Neurodegeneration
Novel Systems and Emerging Concepts

Molecular Neurodegeneration
Basic biology and disease pathways

News from Alzforum

In Small Trial, EH301 Appears to Halt Progression of ALS

Immune Cells Clog Capillaries in Mice, Disrupt Memory

Studies Point to DNA Difficulties in ALS/FTD

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Molecular Neurodegeneration

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