Molecular Neurodegeneration

Featured video: The role of non-coding RNAs in Alzheimer’s disease

Video abstract summarizing new research published in Molecular Neurodegeneration. "Dissecting the role of non-coding RNAs in the accumulation of amyloid and tau neuropathologies in Alzheimer’s disease", De Jager et al. 2017

Content type: Research article
| 17 October 2018

Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis

Authors: Takae Kiyama, Ching-Kang Chen, Steven W Wang, Ping Pan, Zhenlin Ju, Jing Wang, Shinako Takada, William H Klein and Chai-An Mao
Content type: Research article
| 16 October 2018

Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice

Authors: Sander Beel, Sarah Herdewyn, Raheem Fazal, Mathias De Decker, Matthieu Moisse, Wim Robberecht, Ludo Van Den Bosch and Philip Van Damme
Content type: Research article
| 12 October 2018

Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology

Authors: Annerieke Sierksma, Ashley Lu, Evgenia Salta, Elke Vanden Eynden, Zsuzsanna Callaerts-Vegh, Rudi D’Hooge, David Blum, Luc Buée, Mark Fiers and Bart De Strooper
Content type: Research article
| 11 October 2018

ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans

Authors: Olivia J Conway, Minerva M Carrasquillo, Xue Wang, Jenny M Bredenberg, Joseph S Reddy, Samantha L Strickland, Curtis S Younkin, Jeremy D Burgess, Mariet Allen, Sarah J Lincoln, Thuy Nguyen, Kimberly G Malphrus, Alexandra I Soto, Ronald L Walton, Bradley F Boeve, Ronald C Petersen…
Content type: Research article
| 4 October 2018

Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease

Authors: Erik C. B. Johnson, Eric B. Dammer, Duc M. Duong, Luming Yin, Madhav Thambisetty, Juan C. Troncoso, James J. Lah, Allan I. Levey and Nicholas T. Seyfried

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Content type: Research article
| 24 August 2012

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Authors: Karin M Danzer, Lisa R Kranich, Wolfgang P Ruf, Ozge Cagsal-Getkin, Ashley R Winslow, Liya Zhu, Charles R Vanderburg and Pamela J McLean
Content type: Research article
| 12 April 2007

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1polymorphisms

Authors: Suzanne E Wahrle, Aarti R Shah, Anne M Fagan, Scott Smemo, John SK Kauwe, Andrew Grupe, Anthony Hinrichs, Kevin Mayo, Hong Jiang, Leon J Thal, Alison M Goate and David M Holtzman
Content type: Review
| 22 November 2013

Drosophila melanogaster as a model organism for Alzheimer’s disease

Authors: Katja Prüßing, Aaron Voigt and Jörg B Schulz
Content type: Review
| 21 June 2013

Fluid biomarkers in Alzheimer’s disease – current concepts

Authors: Christoffer Rosén, Oskar Hansson, Kaj Blennow and Henrik Zetterberg
Content type: Review
| 15 November 2007

The Alzheimer's disease β-secretase enzyme, BACE1

Authors: Sarah L Cole and Robert Vassar

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Editors-in-Chief

Guojun Bu, Mayo Clinic, USA
Huaxi Xu, Sanford Burnham Prebys Medical Discovery Institute, USA

Aims and scope

Molecular Neurodegeneration is an open access, peer-reviewed journal that encompasses all aspects of neurodegeneration research at the molecular and cellular levels.

Society partner

Molecular Neurodegeneration is the official journal of the BrightFocus Foundation.

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The 5^th international conference on Molecular Neurodegeneration
ICMN 2018: Overlapping Pathologies and Common Mechanisms

June 11 – 13, 2018

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News from Alzforum

Crystal Structure of Aβ and Proposed Receptor Solved

16 October 2018
Mixed Messages: mRNA Splicing Errors May Promote Alzheimer’s

13 October 2018
Intelligence Matters More for Brain Reserve, but Education Helps

12 October 2018

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2016

Thematic series
Molecular Neurodegeneration
Novel Systems and Emerging Concepts
Molecular Neurodegeneration
Collection published: 7 December 2016

2014

Thematic series
Molecular Neurodegeneration
Basic biology and disease pathways
Molecular Neurodegeneration
Collection published: 12 September 2014

Molecular Neurodegeneration

Featured video: The role of non-coding RNAs in Alzheimer’s disease

Articles

Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis

Progranulin reduces insoluble TDP-43 levels, slows down axonal degeneration and prolongs survival in mutant TDP-43 mice

Deregulation of neuronal miRNAs induced by amyloid-β or TAU pathology

ABI3 and PLCG2 missense variants as risk factors for neurodegenerative diseases in Caucasians and African Americans

Deep proteomic network analysis of Alzheimer’s disease brain reveals alterations in RNA binding proteins and RNA splicing associated with disease

Exosomal cell-to-cell transmission of alpha synuclein oligomers

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1polymorphisms

Drosophila melanogaster as a model organism for Alzheimer’s disease

Fluid biomarkers in Alzheimer’s disease – current concepts

The Alzheimer's disease β-secretase enzyme, BACE1

Latest Tweets

Editors-in-Chief

Aims and scope

Society partner

Upcoming conference

News from Alzforum

Crystal Structure of Aβ and Proposed Receptor Solved

Mixed Messages: mRNA Splicing Errors May Promote Alzheimer’s

Intelligence Matters More for Brain Reserve, but Education Helps

Latest collections

2016

2014

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2017 Journal Metrics

Molecular Neurodegeneration

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