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Table 1 Tau sites phosphorylated by GSK-3β.

From: Tau phosphorylation by GSK-3β promotes tangle-like filament morphology

sites Reynoldsa Connellb Rankinc
T175 +   *
T181 +   *
S199 + + +
T205    +
T212 + + +
S214    +
T217 + + +
T231 + + +
S235 + + *
S262    +
S356    +
S396 + + +
S400 + + +
S404 + + +
S409    +
S422    
  1. Identification of in vitro phosphorylated sites by mass spectrometry
  2. a Reynolds, et al. study [37]
  3. b Connell, et al. study [38]
  4. c Identification of in vitro phosphorylated sites by phosphorylation site-specific antibodies. Antibodies were unavailable for those sites marked with an asterisk. S422, not identified by either mass spectrometry or antibody analysis, was a negative control.