Table 1 Ginkgolide B does not affect PGE2-induced loss of synaptophysin.
From: Ginkgolides protect against amyloid-β1–42-mediated synapse damage in vitro
Synaptophysin content (units) | |||
|---|---|---|---|
Pre-treatment | |||
None | Ginkgolide B (1 μM) | AH13205 (100 nM) | |
None | 100 ± 5 | 101 ± 3 | 102 ± 3 |
Aβ 1–42 (200 nM) | 24 ± 4 | 93 ± 7 | 97 ± 6 |
PAF (10 nM) | 33 ± 7 | 78 ± 5 | 89 ± 8 |
PGE 2 (40 nM) | 41 ± 6 | 44 ± 7 | 96 ± 4 |
Butaprost (1 μM) | 29 ± 5 | 37 ± 11 | 94 ± 7 |
Misprostal (1 μM) | 32 ± 7 | 34 ± 6 | 98 ± 5 |