Figure 5
From: Increased DJ-1 expression under oxidative stress and in Alzheimer's disease brains
DJ-1 is detected in both neurons and astrocytes by multiple antibodies. Antibody DJ-1-N (A) has stronger neuronal staining than three commercially available DJ-1 antibodies, E2.19 (C), KAM-SA100 (E), and Park7 (G) that also detected DJ-1 in neurons in all adjacent briefly fixed sections of the same AD patient. DJ-1-N (B), E2.19 (D), and KAM-SA100 (F) detected immunoreactivity in astrocytes in routinely fixed sections, and Park7 showed a much weaker staining of astrocytes (H). Magnification: 20×.