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Figure 4 | Molecular Neurodegeneration

Figure 4

From: Parkinson's disease brain mitochondria have impaired respirasome assembly, age-related increases in distribution of oxidative damage to mtDNA and no differences in heteroplasmic mtDNA mutation abundance

Figure 4

Distributions of heteroplasmic mutations in sPD and CTL brain mtDNA. mtDNA's from six sPD and six CTL brains were amplified using primer pairs A-H. The amplicons were subject to Surveyor Nuclease treatment and separation/analysis of products using Experion 12K DNA chips. Bands from 1000-1900 bp size are included in the Figure. The Y-axes are DNA levels and X-axes are product sizes in bp.

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