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Figure 6 | Molecular Neurodegeneration

Figure 6

From: Parkinson's disease brain mitochondria have impaired respirasome assembly, age-related increases in distribution of oxidative damage to mtDNA and no differences in heteroplasmic mtDNA mutation abundance

Figure 6

Levels of mtDNA and PGC-1α expression in sPD and CTL brain homogenates. mtDNA D-loop was assayed with qPCR in genomic DNA's and PGC-1α expression was assayed with qPCR in cDNA's derived from sPD and CTL brain total homogenates and normalized to 18S rRNA levels. Their relationship was best described by a two-variable rectangular hyperbola shown in C.

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Molecular Neurodegeneration

ISSN: 1750-1326