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Table 2 UCHL1 genotype and allele frequencies in patients with AD and controls

From: Ubiquitin carboxy-terminal hydrolase L1 (UCHL1) S18Y polymorphism in Alzheimer's disease

UCHL1genotype
frequencies, n (%)
AD patients (n = 452) Controls (n = 234) P-value*
AA 15 (3.3) 6 (2.6) 0.649
AC 112 (24.8) 77 (32.9) 0.030
CC 325 (71.9) 151 (64.5) 0.054
UCHL1 allele frequencies, n (%)    
allele A 142 (15.7) 89 (19.0) 0.128
allele C 762 (84.3) 379 (81.0)  
UCHL1 allele A-carrier n (%) 127 (28.1) 83 (35.5) 0.054
UCHL1 allele C-carrier n (%) 437 (96.7) 228 (97.4) 0.649
  1. *Fisher's Exact Test, There are two alleles per subject, yielding n = 904 for AD patients and n = 468 for controls. AD = Alzheimer's disease.