Attenuation of Aβ
-induced vessel constriction by ROS scavenging. Cerebral arterioles were incubated with 100 nmol/L Aβ1-40 and/or the ROS scavenger MnTBAP. MnTBAP reduced Aβ1-40-induced vessel constriction at 100 μmol/L indicating that the Aβ effect is partially due to reactive oxygen species. * denotes p < 0.05 from Aβ alone (n = 3). MnTBAP itself had no effect on the vessel diameter (n = 5).