Skip to main content
Figure 5 | Molecular Neurodegeneration

Figure 5

From: Prolonged Aβ treatment leads to impairment in the ability of primary cortical neurons to maintain K+ and Ca2+ homeostasis

Figure 5

Kinetics of Ca2+ fluxes in response to acute application of 10 μM glutamate. Ca2+ fluxes were measured from age-similar control cells (A) and primary cortical neurons treated daily with 1 μM Aβ1-40 for six days (B). Flux values were recorded for 5 min before glutamate application (-5 to 0 min) and 25 min afterwards with data acquired at a rate of 10 samples/sec and averaged over every 6 sec. Glutamate (10 μM) was applied at zero time as indicated by an arrow and led to Ca2+ influx into cultured cortical neurons (positive flux values). One (out of 7) typical example is shown.

Back to article page

Molecular Neurodegeneration

ISSN: 1750-1326