Skip to main content
Figure 1 | Molecular Neurodegeneration

Figure 1

From: BACE1-/- mice exhibit seizure activity that does not correlate with sodium channel level or axonal localization

Figure 1

Electoencephalogram (EEG) activity in BACE1+/+ and BACE1-/- mice. A. Background spontaneous EEG activity in a BACE1+/+ and BACE1-/- mouse. B. Background EEG activity in BACE1-/- mouse displays multiple epileptiform abnormalities. SWD, spike-wave discharge. C. EEG activity during a generalized tonic-clonic seizure in a BACE1-/- mouse. D. Number of spike-wave discharges (SWDs) per hour observed in BACE1-/- mice following administration of 100 mg/kg of ethosuximide or 25 mg/kg of phenytoin; n = 4; **p < 0.01.

Back to article page

Molecular Neurodegeneration

ISSN: 1750-1326