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Figure 2 | Molecular Neurodegeneration

Figure 2

From: Abnormal iron metabolism in fibroblasts from a patient with the neurodegenerative disease hereditary ferritinopathy

Figure 2

Increased levels of ferritin polypeptides in HF skin fibroblasts. a) Representative western blot showing the expression of ferritin subunits in non-HF and HF fibroblasts. Western blot was carried out using antibodies against ferritin heavy chain (FTH), the amino terminus of ferritin light chain (FTL) that recognizes wild-type and mutant FTL subunits, and abs specific for the mutant subunit (MT-FTL). b) Densitometric analysis of ferritin subunit protein levels shows increased levels of FTH and wild-type and mutant FTL. Results are the means and SD of three independent experiments (*p < 0.05).

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Molecular Neurodegeneration

ISSN: 1750-1326