Figure 6From: Abnormal iron metabolism in fibroblasts from a patient with the neurodegenerative disease hereditary ferritinopathyOxidative stress in HF skin fibroblasts. Fibroblasts were grown in standard culture medium and then cultured for 72 h in medium containing 100 μM FAC. Cells were subsequently loaded with DHCF-DA and DCF fluorescence was determined. Significantly higher levels of ROS were observed in HF fibroblasts under basal conditions. After FAC treatment, HF fibroblasts showed significantly higher levels of ROS than wild-type fibroblasts. *p < 0.05.Back to article page