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Figure 5 | Molecular Neurodegeneration

Figure 5

From: A hereditary spastic paraplegia mutation in kinesin-1A/KIF5A disrupts neurofilament transport

Figure 5

Summary of kinetic data. Bar graphs summarizing the kinetics of neurofilament movement in axons of cortical neurons expressing GFP-NFM alone, GFP-NFM plus N256S-kinesin-1A, or GFP-NFM plus exogenous wild type kinesin-1A. Graphs A-D summarize the data in Figure 3 and graphs E-J summarize the data in Figure 4. The asterisks denote the p values comparing the GFP-NFM plus N256S-kinesin-1A and the GFP-NFM plus exogenous wild type kinesin-1A to GFP-NFM alone (Mann-Whitney test: *** = p < 0.005; ** = p < 0.01; * = p < 0.05).

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