rPrPSc shown in histoblots of coronal sections through the dorsal hippocampus where it overlies the thalamus. Samples were taken from RML-infected mice at 93 dpi untreated (A) and treated with GSI + Qa for 43 days (B). CC, corpus callosum; f, fimbria of fornix; Hp, hippocampus; IC, internal capsule; Nc, neocortex; Th, thalamus. Adapted from Spilman et al. .