Figure 2

Schematic representation of α-synuclein/eGFP constructs. (A) Schematic of wild-type α-syn with C-terminal eGFP fusion; coding exons are depicted as blue boxes numbered 2 to 6. Positions of two PD-associated mutations (A30 and A53) are indicated, and black lines represent the predicted secondary structure in the presence of lipid. (B) Exon deletion mutants; crosshatched boxes represent deleted regions.