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Table 4 Analysis of covariance of PGC1α rs2970870 in HD patients with ≤ 55 CAGs

From: Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease

Model R2 ΔR2 P value
HD CAG 0.3807   < 0.0001*
HD CAG + PGC1α rs2970870    
   1-1 vs 1-2 vs 2-2 0.3857 0.0050 0.0435*
   1-1 vs 1-2 + 2-2 0.3808 0.0001 0.7566
  1. The level of significance was set to P = 0.05; n = 784
  2. HD CAG expanded CAG allele in huntingtin