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Figure 1 | Molecular Neurodegeneration

Figure 1

From: Impairment of brain endothelial glucose transporter by methamphetamine causes blood-brain barrier dysfunction

Figure 1

METH inhibits glucose uptake in hBEC. (A) Dose dependent Effect of METH on D-(2-3H)-glucose uptake in hBECs for 24 hr. (B) Effect of METH (20 μM and 200 μM) on D-(2-3H)-glucose uptake in hBECs with or without GLUT1 inhibitor cytochalasin B (CB, 10 μM) and acetyl-L-carnitine (ALC, 200 μM) for 24 hr. (C) Effect of METH on D-(2-3H)-glucose uptake in hBECs at 24, 48 and 72 hr exposure periods and compared with untreated control cells. *p < 0.05, **p < 0.01 statistically significant compared with controls.

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