Pleiotrophin over-expression rescues TH-immunoreactive terminals in the striatum. (A) Tyrosine hydroxylase-immunoreactive (TH-ir) area in the 6-OHDA or vehicle injected striatum of Adβgal and AdPTN treated animals (percent of contralateral side). Sham/Adβgal: 90 ± 1%, Sham/AdPTN: 90 ± 1%, 6-OHDA/Adβgal: 53 ± 3%, 6-OHDA/AdPTN: 63 ± 2%. Student Neuman Keuls post hoc test, after significant interaction in a two-way ANOVA and Logit transformation of the variable , *p< 0.05. Mean ± SEM. (B) Outlines on photomicrographs illustrate the area used for optical density measurements on a representative coronal section of the striatum (+0.20 mm from bregma). Scale bar: 500 μm.