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Figure 7 | Molecular Neurodegeneration

Figure 7

From: Molecular interplay between leptin, insulin-like growth factor-1, and β-amyloid in organotypic slices from rabbit hippocampus

Figure 7

Inhibition of mTORC1 with rapamycin prevents IGF-1-induced increase in leptin expression levels. (a) Representative Western blot, (b) densitometric analyses, (c) ELISA immunoassay analysis, and (d) Real time RT-PCR show that treatment of organotypic slices with IGF-1 for 72 hours significantly increases basal expression levels of leptin but fails to prevent the reduction of leptin expression levels induced by rapamycin. ***p < 0.001 versus control.

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Molecular Neurodegeneration

ISSN: 1750-1326