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Table 2 BBC3 is important for developmental cell death in the brain.

From: BBC3 (PUMA) regulates developmental apoptosis but not axonal injury induced death in the retina

  

Brain weight (mg)

Body weight (g)

Males

Bbc3 +/+

448 ± 5

20.7 ± 0.5

 

Bbc3 -/-

512 ± 16*

18.8 ± 0.4

Females

Bbc3 +/+

433 ± 15

17.0 ± 0.8

 

Bbc3 -/-

497 ± 11*

17.0 ± 0.9

  1. All mice used were between 52 and 64 days old. *, P < 0.005 compared to Bbc3+/+ of same sex and the effect remains after adjusting for body weight (P < 0.001). N>5 for each sex and genotype.
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Molecular Neurodegeneration

ISSN: 1750-1326