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Figure 2 | Molecular Neurodegeneration

Figure 2

From: Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1α) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis

Figure 2

PGC-1α improved motor performance and survival in SOD1 mutant mice. (A) Motor performance as measured by rotarod test in WT, PGC-1α, SOD1-G93A and SOD1-G93A/PGC-1α animals (**p < 0.01); (B) Survival analysis of WT, PGC-1α, SOD1-G93A and SOD1-G93A/PGC-1α animals (**p < 0.01 by Mantel-Cox test); (C) Average body weight of WT, PGC-1α, SOD1-G93A and SOD1-G93A/PGC-1α animals; (D) Average weight loss (percentage of peak weight) of SOD1-G93A and SOD1-G93A/PGC-1α animals (*p < 0.05).

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Molecular Neurodegeneration

ISSN: 1750-1326