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Table 1 MPTP-treated animal subjects.

From: Upregulation of cathepsin D in the caudate nucleus of primates with experimental parkinsonism

Animal

Total MPTP (mg/kg)

Weeks since first treatment

Weeks since last dose

Final Kurlan score

543

4.1

31

7

3

547

4.1

31

7

3

549

2.7

23

8

6.5

  1. Animals received intermittent low-dose MPTP as indicated in Figure 1. The total dose of MPTP received by each animal, total time since first treatment, the time between the last dose and animal sacrifice, and the clinical score at sacrifice is indicated.