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Table 2 Proteins specifically altered in FTLD-U urea fractions using two independent proteomics strategies.

From: Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration

  GeneBank™ Label-Free Approach CDIT Approach
Protein Accession Number mean Log2Ratio Log2Ratio
   FTLD-U/Control FTLD-U/AD FTLD-U/Control
Septin 11 NP_060713.1 2.0 2.4 1.8
Excitatory Amino Acid Transporter 2 NP_004162.2 2.0 1.5 4.2
Glial Fibrillary Acidic Protein NP_002046.1 1.9 1.3 2.2
Alpha Catenin NP_001894.2 1.3 1.3 3.9
Aquaporin 4 NP_004019.1 1.1 0.9 10.1
Protein Phosphatase 2 NP_055040.2 1.0 1.2 1.8
Transketolase NP_001055.1 0.9 1.1 2.2
2,4-Dienoyl CoA Reductase 2 NP_065715.1 -1.1 -0.9 -3.2
Rho GTPase Activating Protein 1 NP_004299.1 -1.5 -1.0 -1.6
Synaptosomal-Associated Protein 25 NP_003072.2 -1.5 -1.0 -4.9