Table 2 Proteins specifically altered in FTLD-U urea fractions using two independent proteomics strategies.
From: Aberrant septin 11 is associated with sporadic frontotemporal lobar degeneration
| Â | GeneBankâ„¢ | Label-Free Approach | CDIT Approach | |
|---|---|---|---|---|
Protein | Accession Number | mean Log2Ratio | Log2Ratio | |
| Â | Â | FTLD-U/Control | FTLD-U/AD | FTLD-U/Control |
Septin 11 | NP_060713.1 | 2.0 | 2.4 | 1.8 |
Excitatory Amino Acid Transporter 2 | NP_004162.2 | 2.0 | 1.5 | 4.2 |
Glial Fibrillary Acidic Protein | NP_002046.1 | 1.9 | 1.3 | 2.2 |
Alpha Catenin | NP_001894.2 | 1.3 | 1.3 | 3.9 |
Aquaporin 4 | NP_004019.1 | 1.1 | 0.9 | 10.1 |
Protein Phosphatase 2 | NP_055040.2 | 1.0 | 1.2 | 1.8 |
Transketolase | NP_001055.1 | 0.9 | 1.1 | 2.2 |
2,4-Dienoyl CoA Reductase 2 | NP_065715.1 | -1.1 | -0.9 | -3.2 |
Rho GTPase Activating Protein 1 | NP_004299.1 | -1.5 | -1.0 | -1.6 |
Synaptosomal-Associated Protein 25 | NP_003072.2 | -1.5 | -1.0 | -4.9 |