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Table 2 Amyloid binding affinities (KD) of resorufin analogs

From: Resorufin analogs preferentially bind cerebrovascular amyloid: potential use as imaging ligands for cerebral amyloid angiopathy

Compound name

On CAA

(nM)

On neuritic

plaques (nM)

Resorufin

874 ± 177

> 10,000

Ethoxyresorufin

247 ± 135

> 10,000

Benzyloxyresorufin

Methoxy-X34

473 ± 82

325 ± 39

> 10,000

219 ± 86