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Figure 1 | Molecular Neurodegeneration

Figure 1

From: Adeno-associated virus-mediated brain delivery of 5-lipoxygenase modulates the AD-like phenotype of APP mice

Figure 1

AAV1/2-5LO over-expression modulates behavioral deficits of Tg2576 mice. A. Number of total arm entries for AAV1/2-5LO and AAV-empty vector control treated Tg2576 and wild type (WT) mice. B. Contexual fear memory response in AAV1/2-5LO and empty vector treated Tg2576 and wild type (WT) mice. C. Percentage of alternations between AAV-5LO and AAV-empty vector (*p < 0.01). D. Cued fear memory response in AAV1/2-5LO and empty vector injected Tg2576 and wild type (WT) mice. Values represent mean ± SEM; *p < 0.01; n = 10 AAV1/2-5L0; n = 8 empty vector.

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Molecular Neurodegeneration

ISSN: 1750-1326