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Figure 6 | Molecular Neurodegeneration

Figure 6

From: Aggregation, impaired degradation and immunization targeting of amyloid-beta dimers in Alzheimer’s disease: a stochastic modelling approach

Figure 6

Effect of varying parameter values on plaque formation. A k dimer , B k pf , C k pg , D k pghalf . Each point shows the percentage number of cells associated with plaques at age 100 years from 500 simulations. The error bars show 95% confidence intervals for the percentages. The dashed vertical line indicates the default parameter value. In B the x-axis is plotted on a log scale as the parameter values were varied over four orders of magnitude. In A and C the x-axis is plotted on a log scale as the parameter values were not linearly spaced.

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