Table 3 List of reactions for Model 2
Reaction id | Reactants | Products | Kinetic rate law |
|---|---|---|---|
AbetaProduction | Source | Abeta | k prod |
AbetaDegradation | Abeta | Sink | k deg Abeta (Normal rate) |
k deg Abeta * Nep (AD rate) | |||
Dimerisation | 2Abeta | AbDim | k dimer Abeta*(Abeta-1)*0.5 |
Dedimerisation | AbDim | 2Abeta | k dedimer AbDim |
PlaqueFormation | AbDim | AbP | k pf AbDim*(AbDim-1)*0.5 |
PlaqueGrowth | Abeta, AbP | 2AbP | k pg Abeta*(AbP2/(k pghalf 2 + AbP2)) |
Disaggregation | AbP | Abeta | k disagg AbP |
NeprilysinDegradation | Nep | Sink | k degNep *Nep |