Figure 2
From: Blood–brain-barriers in aging and in Alzheimer’s disease
BCSFB composition, function and alterations in aging and AD. (A) The CP is formed by a monolayer of epithelial cells originating in the ependymal cells that line the brain ventricles, forming a closed structure – the stroma. (B) CP produces CSF. CP epithelial cells contain transporters and receptors in both the basolateral and apical sides. (C) Several alterations are observed at the epithelial cells of the BCSFBB during aging and in AD.