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Figure 1 | Molecular Neurodegeneration

Figure 1

From: Abundance of Aβ5-xlike immunoreactivity in transgenic 5XFAD, APP/PS1KI and 3xTG mice, sporadic and familial Alzheimer’s disease

Figure 1

Analysis of the AB5-3 using dot blotting. Full length and N-truncated amyloid-β peptides were probed and spotted into a nitrocellulose membrane. (A) After incubation with the primary antibody AB5-3 only the Aβ5–42 variant was recognized indicating specificity for this peptide. (B) The pan-Aβ antibody 24311 recognized all Aβ variants demonstrating that all peptides were available.

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