Figure 1From: Abundance of Aβ5-xlike immunoreactivity in transgenic 5XFAD, APP/PS1KI and 3xTG mice, sporadic and familial Alzheimer’s diseaseAnalysis of the AB5-3 using dot blotting. Full length and N-truncated amyloid-β peptides were probed and spotted into a nitrocellulose membrane. (A) After incubation with the primary antibody AB5-3 only the Aβ5–42 variant was recognized indicating specificity for this peptide. (B) The pan-Aβ antibody 24311 recognized all Aβ variants demonstrating that all peptides were available.Back to article page