Table 1 Demographic data and semiquantitative analysis of antibody stainings in SAD, FAD and non-demented control cases
Case | Age | Gender | Braak stage | Aβ5-x | Aβ | ||
|---|---|---|---|---|---|---|---|
SP | CAA | SP | CAA | ||||
Sporadic AD cases: | |||||||
AD-1 | 88 | F | IV | + | - | +++ | ++ |
AD-2 | 84 | F | IV | + | - | +++ | - |
AD-3 | 86 | M | IV | + | ++ | ++ | +++ |
AD-4 | 88 | F | IV | + | - | ++ | - |
AD-5 | 84 | F | IV | + | ++ | +++ | ++ |
AD-6 | 93 | M | IV | - | + | ++ | +++ |
AD-7 | 92 | M | IV | - | + | +++ | ++ |
AD-8 | 92 | F | IV | + | ++ | +++ | +++ |
AD-9 | 91 | F | IV | + | ++ | +++ | +++ |
AD-10 | 91 | M | IV | + | + | ++ | +++ |
AD-11 | 92 | F | IV | - | + | ++ | +++ |
AD-12 | 91 | F | IV | - | - | +++ | ++ |
Non-demented control cases: | |||||||
NDC-1 | 70 | M | 0 | - | - | - | - |
NDC-2 | 90 | F | I | + | + | ++ | ++ |
NDC-3 | 88 | F | I | + | - | ++ | - |
NDC-4 | 73 | M | 0 | - | - | - | - |
NDC-5 | 91 | M | I | - | - | - | - |
NDC-6 | 78 | F | I | + | - | ++ | - |
NDC-7 | 84 | M | I | - | - | - | - |
NDC-8 | 78 | M | I | + | - | ++ | ++ |
NDC-9 | 82 | F | I | - | - | - | - |
Familial AD cases | |||||||
APPE693G | 64 | M | n.a. | ++ | ++ | +++ | +++ |
APPKM670/671NL | 61 | F | n.a. | ++ | ++ | +++ | +++ |
PS1∆Ex9 | 69 | M | n.a. | ++ | + | +++ | + |
PS1∆Ex9 | 61 | M | n.a. | ++ | ++ | +++ | + |
PS1∆Ex9 | 64 | M | n.a. | + | + | +++ | + |