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Figure 1 | Molecular Neurodegeneration

Figure 1

From: Optic nerve crush induces spatial and temporal gene expression patterns in retina and optic nerve of BALB/cJ mice

Figure 1

Temporal changes of specific retinal gene clusters related to neuronal loss and regeneration failure. Neuron specific and axonal regeneration related neuronal clusters were selected from the retinal GO tables; and the microarray ratios of the genes within each of these clusters were graphed temporally (0 to 28 days post crush (dpc)). Neuronal clusters identified included (A) neuron projection, (B) regulation of axonogenesis, (C) neuron projection morphogenesis, (D) neuron differentiation and (E) axon. Significance of these clusters was determined using the Benjamini multiple test correction, GO enrichment score χ2 test and Fishers Exact test (p < 0.05).

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