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Figure 4 | Molecular Neurodegeneration

Figure 4

From: Gene expression changes consistent with neuroAIDS and impaired working memory in HIV-1 transgenic rats

Figure 4

Hierarchical clustering of top differentially expressed genes in the hippocampus of HIV-1 Tg rats (HIV) versus wild-type littermate controls (Control). Gene expression was profiled in the hippocampi of HIV-1 and wild-type rats with high-density Affymetrix microarrays. The dendrogram shows 73 of the top 100 differentially expressed probesets that were found to be associated with gene names (Additional file 3: Table S3). Genes are colored according to their expression values. Red indicates upregulated genes in HIV-1 Tg rats, while blue indicates downregulated genes. Brightness is proportional to the extent of change in gene expression.

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Molecular Neurodegeneration

ISSN: 1750-1326