Figure 8
From: Motor and cognitive deficits in aged tau knockout mice in two background strains
Genetic background varies behaviors of mice at 12-months of age in Y maze test. a) Novel arm duration time (% time spent in novel arm during 5 mins recording time) of Y maze test. Two-way ANOVA: interaction (p = 0.04), but no genetic background (p = 0.664), or genotype (p = 0.182) effects. Additional one-way ANOVA were performed to determine if genotype accounts for variance in Bl6/129sv group. b) Total distance of movement during the test. Two-way ANOVA: interaction (p = 0.002) and genotype effect (p = 0.025), but no genetic background effect (p = 0.093). c) Velocity of movement during the test. Two-way ANOVA: interaction (p = 0.003) and genotype effect (p = 0.005), but no genetic background effect (p = 0.157). *p < 0.05, **p < 0.01, versus age-matched wild type mice (Bonferroni post hoc test). n is indicated in the column of each group. Gender distribution is given in Additional file 6: Table S1. Data are means ± SEM.