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Table 3 Logistic regression modeling of rs3851179 and/or rs588076 effect(s) on AD

From: An intronic PICALM polymorphism, rs588076, is associated with allelic expression of a PICALMisoform

Model

SNP

Odds Ratio

Confidence Interval

P value

rs588076

rs588076

0.8413

0.7151 - 0.9898

0.0372

rs3851179

rs3851179

0.7786

0.6819 - 0.8891

0.0002

rs3851179 + rs588076

rs3851179

0.7767

0.6604 - 0.9136

0.0023

rs3851179 + rs588076

rs588076

1.005

0.8238 - 1.227

0.959

  1. In addition to the indicated SNPs, these models were adjusted for age of onset, APOE alleles, sex and contributing center.
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Molecular Neurodegeneration

ISSN: 1750-1326