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Figure 2 | Molecular Neurodegeneration

Figure 2

From: Altered synaptic structure in the hippocampus in a mouse model of Alzheimer’s disease with soluble amyloid-β oligomers and no plaque pathology

Figure 2

Alterations in neuronal morphology with amyloid pathology. Representative neuronal traces of WT and DU neurons and their apical and basal dendrograms are represented in A and B, respectively. Significant differences were observed in apical but not basal length (C and D). Sholl analysis revealed a significant decrease in apical dendritic length (E) and intersections at 120 μm and 150 μm away from the soma, respectively, in DU neurons compared to WT (G), but this finding was not repeated for basal dendrites (F, H). Data represent group mean ± SEM (n = 11 WT and 5 DU). *p < 0.05.

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Molecular Neurodegeneration

ISSN: 1750-1326