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Figure 6 | Molecular Neurodegeneration

Figure 6

From: Amyloid peptides ABri and ADan show differential neurotoxicity in transgenic Drosophila models of familial British and Danish dementia

Figure 6

Accumulation of amyloid peptides in the retina. A, paraffin sections of the retina stained with H&E showing disorganization of ommatidia (arrows). Scale bar = 25 μm. B, horizontal sections from the retina of transgenic lines: GMR-GAL4/Aβ42 × 2, GMR-GAL4/ABri × 2 andGMR-GAL4/ADan x 2 were immunostained with 6E10, anti-ABri and anti-ADan, respectively and sections from GMR-GAL4/Bri2-23 x 2 control lines probed with the amyloid peptide-specific antibodies. Arrows indicate immunoreactivity consistent with amyloid peptide deposits. Images represent the results of at least 2 independent biological experiments. Scale bar = 20 μm.

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