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Figure 4 | Molecular Neurodegeneration

Figure 4

From: SNAP-25 is a promising novel cerebrospinal fluid biomarker for synapse degeneration in Alzheimer’s disease

Figure 4

ROC curve analysis of SNAP-25 in human CSF. ROC curve analysis for SNAP-25 32-40 (turquoise), SNAP-25 17-31 (green), SNAP-25 Ac-2-16 (black) Aβ1-42 (orange), T-tau (purple) and P-tau181 (yellow) in CSF for differentiation of Alzheimer’s disease patients from controls in the entire subject material. The area under the curve (95% confidence interval) was 0.901 (0.828-0.974) (P < 0.0001), 0.808 (0.703-0.913) (P < 0.0001), 0.772 (0.659-0.885) (P < 0.001), 0.881 (0.802-0.960) (P < 0.0001), 0.933 (0.873-0.994) (P < 0.0001), and 0.916 (0.844-0.987) (P < 0.0001), respectively.

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