Figure 2
From: Long-term treadmill exercise attenuates tau pathology in P301S tau transgenic mice
Total and phosphorylated tau immunofluorescence is reduced in the spinal cord and brain of P301S transgenic mice after 12-weeks of forced treadmill exercise. Representative images of total (TAU5, A) and phosphorylated tau (AT8, A; AT100 and AT180, B) immunofluorescence in the spinal cord (dorsal horn), cortex (layers I-II), and hippocampus. For spinal cord and cortex images, scale bars represent 100 μm. For hippocampus images, scale bar represents 200 μm. Green = TAU5; red = AT8, AT100, or AT180; blue = DAPI.