Skip to main content
Figure 1 | Molecular Neurodegeneration

Figure 1

From: Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury

Figure 1

Head kinematics during rTBI. Head kinematic parameters during impacts were assessed in 8 mice subjected to rTBI. Data are represented as the means for each impact. (A) Head trajectory during the maximum acceleration phase in the sagittal plane following impact. (B) Head displacement-time graph following impact. (C) Head deflection is measured as the angle between the snout, side marker and the horizontal plane. Linear head velocity and linear head acceleration are depicted in (D) and (E), respectively. (F) and (G) show angular head velocity and angular acceleration, respectively. Data in (A) are represented as mean ± 95% CI in both X- and Y- direction, respectively. Data in B-G are represented as mean ± 95% CI. (H) Summary of peak values of kinematic parameters averaged across all 8 rTBI mice. The coefficient of variation (CV) was calculated as the average of day 1 and day 2 peak values from all available recordings.

Back to article page

Molecular Neurodegeneration

ISSN: 1750-1326