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Figure 7 | Molecular Neurodegeneration

Figure 7

From: Associations between brain microstructures, metabolites, and cognitive deficits during chronic HIV-1 infection of humanized mice

Figure 7

DTI metrics. (A) Brain regions analyzed for DTI metrics. (B) Fractional anisotropy (mean ± SEM) in (top) CA1, CA3, and dentate gyrus (from left to right) and (bottom) frontal cortex, middle cerebral cortex, and splenium of the corpus callosum (from left to right) as shown in (A). (red “*” symbol) p < 0.05 control (n = 7) vs infected (n = 8) mice, +p < 0.05 versus time zero in control mice, (red “+” symbol) p < 0.05 versus pre-infection in HIV-1 infected animals.

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Molecular Neurodegeneration

ISSN: 1750-1326