An automated image analysis method to measure regularity in biological patterns: a case study in a Drosophila neurodegenerative model

Table 1 List of the 18 variables used for the statistical model development

	Variables
Grid-based variables:
Grid-Cells %	N_maxima<2	N_maxima<4	N_maxima<6	N_maxima<8
Maxima per cell	Mean†	Variance†	Skewness†	Total†
Distance to the center of mass	Mean†	Variance†	Skewness†
Kurtosis	Mean	Variance	Skewness
Skewness	Mean	Variance†	Skewness
ROI-based variables:
Nearest Neighbor		Variance†

Each row accounts for a given spatial measurement of the point distribution per grid cell or per ROI. Grid-Cells (%) refers to the percentage of cells with less than a certain number of maxima (2, 4, 6 or 8). Variables marked with † passed the correlation test and were tested in the ANOVA analysis (Table 2).

ISSN: 1750-1326