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Fig. 1 | Molecular Neurodegeneration

Fig. 1

From: Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain

Fig. 1

Generation of transgenic TDP-43 pigs. a The plasmid DNA structure for expressing mutant TDP-43 (M337V) under the human ubiquitin promoter in transgenic pigs. F2A is a peptide sequence that can self-cleave to separate TDP-43 from EGFP in cells. b The numbers of embryos used and transgenic TDP-43 pigs produced. c PCR genotype analysis of ear tissues from 15 transgenic TDP-43 pigs. Two non-transgenic pig (Control) ear tissues served as a control

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Molecular Neurodegeneration

ISSN: 1750-1326