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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Distinct clinical and neuropathological features of G51D SNCA mutation cases compared with SNCA duplication and H50Q mutation

Fig. 5

Glial pathology. a The variable morphology of GCI-like inclusions in all three G51D cases is shown in representative images in which α-synuclein (red) is detected within oligodendrocytes (Olig2, green). b Rare coiled body-like inclusions of α-synuclein (red) are detected within oligodendrocytes (Olig2, green) within the cerebellar white matter of the duplication case. c On rare occasions α-synuclein (green) was confirmed to be present within microglia (Iba-1, red) in G51D cases (arrows) shown at high magnification (inset). Scale bar represents 50 μm

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Molecular Neurodegeneration

ISSN: 1750-1326