Table 2 The comparison of half-life of tau between pro-aggregant mice and anti-aggregant mice
From: Analysis of in vivo turnover of tau in a mouse model of tauopathy
Intracellular soluble tau | ||
half-life (t1/2, day) | R2 | |
Pro-aggregant | 9.7 | 0.91 |
Anti-aggregant | 11.1 | 0.96 |
P | 0.06 | |
Extracellular soluble tau | ||
half-life (t1/2, day) | R2 | |
Pro-aggregant | 17.3 | 0.7 |
Anti-aggregant | 10.9 | 0.91 |
P | 0.25 | |
Intracellular soluble pS202/pT205 tau | ||
half-life (t1/2, day) | R2 | |
Pro-aggregant | 5.7 | 0.8 |
Anti-aggregant | 7.5 | 0.89 |
P | 0.64 | |
Intracellular soluble pS396 tau | ||
half-life (t1/2, day) | R2 | |
Pro-aggregant | 9.8 | 0.51 |
Anti-aggregant | 7.6 | 0.64 |
P | 0.45 | |