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Fig. 5 | Molecular Neurodegeneration

Fig. 5

From: Novel (Hetero)arylalkenyl propargylamine compounds are protective in toxin-induced models of Parkinson’s disease

Fig. 5

The effects of SZV558, SZV2220 and rasagiline (10 mg/kg i.p for 21 days each) on MPTP treated mice striatum using a subchronic (Tatton-Kish) model of PD. The MPTP group received vehicle treatment for the same period after the MPTP treatment. Dopamine content is expressed as pmol/mg protein. Symbols represent significant changes from saline treated (+++ P < 0.001), MPTP treated (***P < 0.001) and rasagiline treated animals, (# P < 0.05), respectively. Statistical analysis: one-way ANOVA followed by the Tukey test. Number of independent experiments: 8-12/group

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Molecular Neurodegeneration

ISSN: 1750-1326