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Table 2 Motility test pre- and post-chronic MPTPp treatment

From: Novel (Hetero)arylalkenyl propargylamine compounds are protective in toxin-induced models of Parkinson’s disease

TOTAL ACTIVITY

 

Pre-treatment

Post-treatment

 

Mean

SEM

Mean

SEM

  Vehicle

11503.75

983.49

8737.50

1651.77

  MPTPp

5803.80

1162.18

6587

771.63

  MPTPp + SZV558

9063.14

1055.95

7904.85

982.36

  MPTPp + Rasagiline

9941.57

1055.57

8867.85

1214.24

LOCOMOTOR ACTIVITY

  Vehicle

8727

983.49

3690.25

1651.77

  MPTPp

4004.60

916.64

2773.40

343.84

  MPTPp + SZV558

6929.85

791.63

3415.86

463.68

  MPTPp + Rasagiline

7497

928.82

3938

639.83

  1. Motor activity was measured 2 days before the first MPTPp administration and 1 day after the last MPTPp administration. Values are expressed as mean ± SEM
  2. Data were statistically compared with one-way ANOVA, followed by the Newman–Keuls post hoc test
  3. Number of independent experiments: 4–7/group
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Molecular Neurodegeneration

ISSN: 1750-1326