Skip to main content

Table 4 Logistic regression analysis of CSF biomarkers between PD and HC

From: Oligomeric and phosphorylated alpha-synuclein as potential CSF biomarkers for Parkinson’s disease

Predictor AUC Sensitivity Specificty p value
t-α-syn 0 · 70 65 % 74 % 0 · 001
p-S129-α-syn 0 · 67 65 % 54 % <0 · 0001
o-α-syn 0 · 77 89 % 52 % < 0 · 0001
p-S129/t-α-syn % 0 · 76 80 % 56 % < 0 · 0001
o-/t-α-syn % 0 · 82 68 % 85 % < 0 · 0001
o-/t-α-syn %, p-S129-α-syn & p-tau 0 · 86 79 % 67 % < 0 · 0001
  1. Abbreviations: t-α-syn total α-synuclein, p-S129-α-syn phosphorylated Ser 129 α-synuclein, o-α-syn oligomeric α-synuclein, p-tau phosphorylated-tau, AUC area under the curve