Deep brain stimulation-associated brain tissue imprints: a new in vivo approach to biological research in human Parkinson’s disease

Table 1 Patient information and clinicopathological data of human BTIs

Patients	Gender	Age, yr	Disease duration, yr	Implanted nuclei	Neurosurgeon	BTI number Left (L) or Right (R)	Experiment
P1	F	41	6	STN	A	L1	SEM
P1	F	41	6	STN	A	R1	CB-IHC
P2	F	60	10	STN	B	L2	CB-IHC
P2	F	60	10	STN	B	R2	CB-IHC
P3	M	52	8	STN	A	L3	P
P3	M	52	8	STN	A	R3	T
P4	M	53	7	STN	B	L4	T
P4	M	53	7	STN	B	R4	T
P5	M	46	6	STN	A	L5	P
P6	M	54	11	STN	B	R6	P
P7	M	61	9	STN	B	L7	P
P7	M	61	9	STN	B	R7	P
P8	M	53	9	GPi	B	L8	P
P8	M	53	9	GPi	B	R8	P
P9	F	45	10	GPi	A	L9	P
P10	M	69	14	GPi	A	L10	P
P11	F	59	12	GPi	A	L11	P
P12	M	52	11	GPi	B	R12	P

Eight men (M) and 4 women (F) had been offered DBS in STN or GPi by neurosurgeon A or B. BTIs were obtained from left (L) or right (R) hemisphere and used for scanning electron microscopy (SEM), cellblock immunohistochemical (CB-IHC), proteomic (P) or transcriptomic (T) analyses

ISSN: 1750-1326