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Table 1 List of commonly dysregulated genes in the cortex and hippocampus of transgenic and wild type mice

From: Vitamin D interacts with Esr1 and Igf1 to regulate molecular pathways relevant to Alzheimer’s disease

   Fold change
   Hipocampus Cortex
Gene symbol Entrez gene name WtVitD/Wt TgVitD/Tg WtVitD/Wt TgVitD/Tg
Ahcy adenosylhomocysteinase −1,73 −2,07 1,79 2,07
Atg4c autophagy related 4C, cysteine peptidase −2,72 −2,75 4,49 4,82
Avp arginine vasopressin −1,59 2,21 1,73 3,96
C130078n14 uncharacterized protein C130078N14 −2,13 −2,17 3,92 2,77
Cdk5rap1 CDK5 regulatory subunit associated protein 1 −1,78 −2,14 2,66 2,92
Cpne1 copine I −1,56 −1,82 1,6 1,71
Dnajb8 DnaJ (Hsp40) homolog, subfamily B, member 8 −1,85 1,98 −1,92 −1,73
Fam205a family with sequence similarity 205, member A 2,34 2,78 1,61 −1,55
Fkbp1a FK506 binding protein 1A, 12kDa 1,97 1,62 −1,72 −1,52
Gbp6 guanylate binding protein family, member 6 2,19 2,21 −2,65 −3,23
Gm4924 predicted gene 4924 1,68 1,94 2,14 1,53
Hla-drb5 major histocompatibility complex, class II, DR beta 5 1,86 1,53 −2,53 −2,34
Iqcf4 IQ motif containing F4 2,74 2,22 −1,54 −1,73
Iqsec3 IQ motif and Sec7 domain 3 −5,23 4,49 −3,3 1,58
Kcnj6 potassium channel, inwardly rectifying subfamily J, member 6 1,61 1,93 −1,79 −1,67
Kdr kinase insert domain receptor −1,6 1,68 1,53 −1,64
Mirg miRNA containing gene −1,91 1,88 −3,41 −1,68
Nanog Nanog homeobox −2,91 1,53 −1,52 −1,66
Ocel1 occludin/ELL domain containing 1 −3,07 −3,98 3,52 3,21
Omp olfactory marker protein −1,54 −10,41 3,18 1,66
Oxt oxytocin/neurophysin I prepropeptide −2,75 4,04 2,03 4,74
Ppp1r16b protein phosphatase 1, regulatory subunit 16B 2,29 2,39 −1,78 −1,78
Prkcd protein kinase C, delta −2,18 −2,52 1,84 1,65
Prl prolactin 1,93 −1,88 10,07 10,54
Rnase4 ribonuclease, RNase A family, 4 1,61 2,12 −2,14 −2,07
Sdc4 syndecan 4 2,38 1,95 −1,91 −1,81
Serpina3g serine (or cysteine) peptidase inhibitor, clade A, member 3G 2,78 1,94 −1,8 −2,42
Znf669 zinc finger protein 669 −2,08 −1,9 1,84 2,2
  1. Dysregulated transcripts in the hippocampus and cortex of vitamin D3 supplemented wild type and transgenic mice in comparison with unsupplemented littermates. The gene symbol, the full name and the fold change of each gene are indicated